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X-ORIGINAL-URL:https://wicane.recherche.univ-lr.fr
X-WR-CALDESC:Évènements pour WiCanE
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250422T080000
DTEND;TZID=Europe/Paris:20250422T170000
DTSTAMP:20260428T133451
CREATED:20250422T100415Z
LAST-MODIFIED:20250701T142255Z
UID:2355-1745308800-1745341200@wicane.recherche.univ-lr.fr
SUMMARY:New WildCan Webinar - July 3\, 2025!!! (invited speaker: Dr. Juan Manuel Vazquez)
DESCRIPTION:We are honored to announce that Dr. Juan Manuel Vazquez will present his exciting research on the “Extensive structural variation and longevity-associated adaptations in Nearctic Myotis bat” at our next WildCan webinar. \nWhen: \nJuly 3rd\, 2025 at 9am MDT / 3 pm CEST (French time) \nHow: \nhttps://cnrs.zoom.us/j/99784448663?pwd=WIIDsGXaIef6sq8Abp8J0L2bQvbCqq.1 \nMeeting ID: 997 8444 8663 \nPassword: zfPq9U \nWhom: \nDr. Juan Manuel Vazquez \nWebsite: https://vazquez.bio/ \nSubject: \nExtensive structural variation and longevity-associated adaptations in Nearctic Myotis bat. \nAbstract: \nThe 100-fold difference in lifespans across mammalian species provides a rich trove of novel pathways and mechanisms underlying exceptional differences in longevity-associated traits such as DNA damage repair. Among mammals\, bats of the genus Myotis exhibit some of the most extreme variations seen in lifespans. To study the evolution of longevity-associated traits\, we generated primary cell lines for over 28 species of bats\, and assembled near-complete diploid genome assemblies for 8 Myotis species. Using genome-wide screens of positive selection\, analyses of structural variation\, and functional experiments in primary cell lines\, we identify new patterns of adaptation contributing to longevity\, cancer resistance\, and viral interactions in bats. We find that Myotis bats have some of the most significant variation in cancer risk across mammals and demonstrate a unique DNA damage response in primary cells of the long-lived M. lucifugus. We also find evidence of extensive structural variation both within and between species\, including in genes central to stress response and viral immunity. Together\, our results demonstrate how genomics and primary cells derived from diverse taxa uncover the molecular bases of extreme adaptations in non-model organisms.
URL:https://wicane.recherche.univ-lr.fr/event/new-wildcan-webinar-invited-speaker-dr-juan-manuel-vazquez/
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240723T080000
DTEND;TZID=Europe/Paris:20240723T170000
DTSTAMP:20260428T133451
CREATED:20240723T125756Z
LAST-MODIFIED:20240723T125901Z
UID:2153-1721721600-1721754000@wicane.recherche.univ-lr.fr
SUMMARY:Postdoctoral position: cancer resistance in wild mammals (cellular and cancer biology)
DESCRIPTION:postdoc_Salamanca_en \n Project information \nCancer is recognized as a pathology that affects almost every member of the animal kingdom. Accurate estimates on cancer in wildlife promise extremely valuable information on oncogenic processes\, as the limited research conducted on non-standard model organisms already provided tremendous insights on the natural mechanisms of cancer resistance. The COVER project proposes to use a multidisciplinary approach at the interface of oncology\, physiology\, cellular and evolutionary biology to characterize the prevalence of cancer in wildlife and identify the genetic\, physiological and life-history predictors of the cross-species pattern of cancer susceptibility. The goal is to unravel the cross-species diversity of cancer resistance\, and highlight future avenues in the identification of efficient tumor-suppressor mechanisms. \nThe project aims at performing in vitro and in vivo functional assays to systematically assess whether and how activation of a driver oncogene results in cell transformation across a panel of cell lines derived from different species. Cancer transformation is a complex process regulated by a concerted cellular response to the homeostatic changes induced by the oncogene and the phenotypic outcome is determined by epigenetic components\, transcriptional modulators and the implementation of tumour-suppressive functions. We will use cell lines from 15 species spanning the entire cancer susceptibility range (from cancer-resistant to highly susceptible species) to evaluate how the propensity for malignant transformation is regulated the molecular and biochemical levels. Also\, we aim at deciphering how those responses are implemented to restrain malignant growth. \nJob requirements \nWe are seeking for a highly motivated postdoc with a strong background in cellular and/or cancer biology and an interest in fundamental and translational cancer research. Proficiency in English\, communication skills and team-work attitude are important requirements. \nApplicants would likely have: \n– A PhD in genetics\, biology\, pharmacology or in a related field of the life sciences. \n– Skills in molecular biology and cell culturing\, including 2D and 3D\, migration assays and experience with the generation of primary cell lines. \n– Previous experience in animal manipulation is a plus\, including experience with cell line implants and small surgery in mice. \n– Prior experience gene screening and editing assays using CRISPR/Cas9 as well as RNAseq data analysis would be an advantage. \nThe position is funded for 2 years by the ANR project COVER (collaboration between the MNHN (Paris\, France)\, LIENSs (La Rochelle\, France\, https://wicane.recherche.univ-lr.fr/) and the CIC (Salamanca\, Spain). The postdoc hired by the MNHN will mostly work at the CIC. The experimental work will be carried out in the laboratory of David Santamaría\, at the Cancer Research Center of Salamanca (Spain). The CIC is a comprehensive research center focused on cancer. It was initiated in 2000 and currently integrates 25 research groups with over 300 researchers/staff grouped in 2 (basic and clinic) research programs. CIC has a primary strategy focused on early cancer development\, diagnosis and therapeutic intervention. \nMore information: https://www.cicancer.org/. \nPlease also see: https://www.cicancer.org/grupo?id=86 \nWe are looking for candidates who could ideally start late 2024 or early 2025 but this could be discussed. \nApplications should be submitted to Bertrand Bed’Hom (bertrand.bedhom@mnhn.fr)\, David Santamaria (d.santamaria@usal.es) and Mathieu Giraudeau (giraudeau.mathieu@gmail.com) and should include a CV with a publication list\, a research statement\, a cover letter and contact information for at least two references (name\, address\, email and phone number).
URL:https://wicane.recherche.univ-lr.fr/event/postdoctoral-position-cancer-resistance-in-wild-mammals-cellular-and-cancer-biology/
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240614T080000
DTEND;TZID=Europe/Paris:20240614T170000
DTSTAMP:20260428T133451
CREATED:20240614T080303Z
LAST-MODIFIED:20240904T143746Z
UID:2135-1718352000-1718384400@wicane.recherche.univ-lr.fr
SUMMARY:Check out our article in "The Conversation"!!!!
DESCRIPTION:Pourquoi les animaux de grande taille développent-ils moins de cancers ?\n\n\nhttps://theconversation.com/pourquoi-les-animaux-de-grande-taille-developpent-ils-moins-de-cancers-230056?utm_source=twitter&utm_medium=bylinetwitterbutton
URL:https://wicane.recherche.univ-lr.fr/event/check-out-our-article-in-the-conversation/
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240611T080000
DTEND;TZID=Europe/Paris:20240611T170000
DTSTAMP:20260428T133451
CREATED:20240611T074426Z
LAST-MODIFIED:20240611T074456Z
UID:2131-1718092800-1718125200@wicane.recherche.univ-lr.fr
SUMMARY:Don’t miss Dr. Murchison’s webinar talk about “Horizonal gene transfer in transmissible cancer”!
DESCRIPTION:When? June 19 @ 2PM CEST \nHow? Zoom link: https://cnrs.zoom.us/j/96821075911?pwd=dG5SRVNrOGJ3Nkt2MzlWZGpjN2RFdz09 \nDr Murchinson’ webpage: https://www.tcg.vet.cam.ac.uk/directory/elizabeth-murchison
URL:https://wicane.recherche.univ-lr.fr/event/dont-miss-dr-murchisons-webinar-talk-about-horizonal-gene-transfer-in-transmissible-cancer/
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240517T080000
DTEND;TZID=Europe/Paris:20240517T170000
DTSTAMP:20260428T133451
CREATED:20240517T081736Z
LAST-MODIFIED:20240517T081736Z
UID:2109-1715932800-1715965200@wicane.recherche.univ-lr.fr
SUMMARY:
DESCRIPTION:Welcome to Simon Mallet\, our new PhD student!! \nSimon has been rewarded a CIFRE thesis in collaboration with Cell Environment on the study of DNA repair mechanisms in relation to cancer resistance in wildlife.  \n@AssoANRT\n@LIENSsCNRSULR\n@WicaneResearch
URL:https://wicane.recherche.univ-lr.fr/event/2109/
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240416T080000
DTEND;TZID=Europe/Paris:20240416T170000
DTSTAMP:20260428T133451
CREATED:20240416T133359Z
LAST-MODIFIED:20240416T134712Z
UID:1866-1713254400-1713286800@wicane.recherche.univ-lr.fr
SUMMARY:Anthony got The Eiffel Excellence Scholarship Program!
DESCRIPTION:Congratulations to Anthony Andrieu\, our PhD student\, on being awarded The Eiffel Excellence Scholarship Program!!!
URL:https://wicane.recherche.univ-lr.fr/event/anthony-got-a-scholarship/
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240410T080000
DTEND;TZID=Europe/Paris:20240410T170000
DTSTAMP:20260428T133451
CREATED:20240723T125437Z
LAST-MODIFIED:20240723T125615Z
UID:2149-1712736000-1712768400@wicane.recherche.univ-lr.fr
SUMMARY:2 year post doc opportunity in comparative oncology\, cancer resistance and somatic mutation rate!
DESCRIPTION:The research teams led by Mathieu Giraudeau (LIENSs\, University of La Rochelle\, France) working on cancer resistance in wild organisms and by Alex Cagan (University of Cambridge\, UK) working on the accumulation of somatic mutations are recruiting a new postdoctoral researcher. The position is fully funded for 2 years by a Chaire d’Excellence Nouvelle Aquitaine to Mathieu Giraudeau. The postdoc hired will spend time in France and the UK (the time spent at each university can be discussed). We are looking for candidates who could ideally start between September and December 2024\, though this is open to discussion. \nmore information here: https://euraxess.ec.europa.eu/jobs/228103 \n  \n  \nPostdoc-ad-Giraudeau-Cagan_English
URL:https://wicane.recherche.univ-lr.fr/event/2-year-post-doc-opportunity-in-comparative-oncology-cancer-resistance-and-somatic-mutation-rate/
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240403T080000
DTEND;TZID=Europe/Paris:20240403T170000
DTSTAMP:20260428T133451
CREATED:20240410T141945Z
LAST-MODIFIED:20240410T142208Z
UID:1663-1712131200-1712163600@wicane.recherche.univ-lr.fr
SUMMARY:Follow us on "X" (Twitter)!
DESCRIPTION: WicaneResearch
URL:https://wicane.recherche.univ-lr.fr/event/follow-us-on-x-twitter/
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